Autoimmune Neuromuscular Diseases

B. Jane Distad, MD

Diagnosis and Treatment of Vasculitic Neuropathy

Despite its heterogeneous clinical presentation, vasculitic neuropathy requires rapid identification and treatment to prevent diagnostic delay or lack of diagnosis.

Anne Møller Witt, MD; Louise Sloth Kodal, MD; and Tina Dysgaard, MedScD

Neuromuscular Sarcoidosis: Peripheral Nervous System Manifestations

A small percentage of individuals with sarcoidosis have peripheral nervous system involvement, manifesting as large-fiber neuropathy, small-fiber neuropathy, or myopathy.

Bénédicte Dansereau, MD, and Leo H. Wang, MD, PhD

Diagnosis of Chronic Inflammatory Demyelinating Polyneuropathy

Due to the heterogeneous presentation of this complex disease, diagnosis is not always straightforward, and proper interpretation of clinical and diagnostic data is crucial to avoid misdiagnosis.

Natalia Gonzalez Caldito, MD, and Ali A. Habib, MD

Diagnosis and Treatment of Lambert-Eaton Myasthenic Syndrome

Recognition of this rare immune-mediated disorder of the neuromuscular junction is critical for treatment, including of potential associated malignancy.

Matthew C. Varon, MD, and Mazen M. Dimachkie, MD

Myasthenia Gravis: Making Progress for More Accurate Diagnoses and Targeted Treatments

Advances in testing and treatments for myasthenia gravis are leading to more accurate diagnoses and improvements in symptom control for individuals with this rare chronic autoimmune disease.

Nicholas J. Silvestri, MD

Adult Inflammatory Myopathies: Updates on Classification and Management

The inflammatory myopathies are classified into homogeneous subtypes on the basis of specific autoantibodies, and management strategies continue to evolve rapidly.

Candie Jammal, MD; Iago Pinal-Fernandez, MD, PhD; and Andrew L. Mammen, MD, PhD

Neuromyelitis Optica Spectrum Disorder With Atypical Imaging Features

We present an unusual, diagnostically challenging case of neuromyelitis optica spectrum disorder with a trident sign and nerve root enhancement on imaging.

Julia Greenberg, MD; Kaiulani Houston, MD, PhD; Kevin Spiegler, MD, PhD; Sujata Thawani, MD, MPH; Harold Weinberg, MD, PhD; and Ilya Kister, MD

Rapidly Progressive Dementia Caused by Neoplastic Meningitis Attributable to Melanoma

We present a case of neoplastic meningitis, manifesting as rapidly progressive dementia, resulting from recurrent metastatic melanoma.

Abdalmalik Bin Khunayfir, MD, and Brian Appleby, MD

The Whole Physician: Addressing Imposter Phenomenon in the Physician Population

Physicians and medical institutions need to take steps to recognize and combat imposter phenomenon, also known as imposter syndrome.

Jill R. Baron, MD, and Jennifer Villwock, MD

Headache Horizons: Headache Pharmacology and Novel Therapeutics Update

Understanding the pharmacokinetics of recently introduced preventive treatments for headache can help the practitioner optimize migraine treatment.

Shivang Joshi, MD, MPH, BPharm

MS Minute: Menopause and Multiple Sclerosis

Multiple sclerosis and menopause have overlapping symptoms, complicating evaluation of disease progression and care of this population.

Denisse Morales-Rodriguez, BS, and Riley Bove, MD, MMSc

Movement Disorders Moment: Environmental and Biologic Risk and Protective Factors Associated with Parkinson Disease

This review provides a concise summary of the evidence for environmental and biologic risk and protective factors for Parkinson disease.

Swati Pradeep, DO, and Jaime M. Hatcher-Martin, MD, PhD

Neuro-Oncology Outlook: Advancements in Targeted Molecular Therapy for Low-Grade Gliomas—Challenging the Treatment Paradigm

Treatment with the IDH inhibitor vorasidenib increased median progression-free survival and time to next intervention in individuals with grade 2 gliomas under surveillance after surgical resection.

Samantha Kropp, MD, and Joe Mendez, MD

About the Cover Artist: Rock Island by Rodrigo Duran

Despite challenges associated with congenital muscular dystrophy and epilepsy, Rodrigo is still pursuing his goal of working in the art industry.